XenoPort Sinks as Spasticity Drug For MS Fails in Trial

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XenoPort Inc., the maker of the drug Horizant for Restless Legs Syndrome, sank the most in almost three years after an experimental medicine failed to meet goals of a late-stage clinical trial.

XenoPort dropped 15 percent to $5.72 at the close in New York, the biggest single-day decline since July 2010. The shares of the Santa Clara, California-based company have declined 26 percent this year.