Lung Cancer Genomic Mapping Yields New Targets in Study
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Mutations within a small cluster of genes tied to tumor growth are involved in three-quarters of the cases of the most common form of lung cancer, according to a study that could help link treatment to specific genetic flaws.
The research is the most comprehensive genomic analysis of adenocarcinoma, a cancer that forms in the tissues near the outer parts of the lungs and is usually linked to smoking, though it can occur in nonsmokers. Researchers identified 18 key mutations in an examination of 230 adenocarcinoma lung tumors, according to the study published today in the journal Nature.