Amgen Therapy Slims Monkeys as Study Seeks Obesity Drug
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An antibody discovered by Amgen Inc. researchers reduces weight and increases glucose tolerance in monkeys, according to a study, potentially opening up a new approach for treating obesity and diabetes in humans.
The obese monkeys lost about 10 percent of their body weight during the 11-week trial, according to the study, which was paid for by Amgen and published today by the journal Science Translational Medicine. The drug also lowered insulin, glucose and triglyceride levels.